The Science of Orgasm: Body & Brain in Action

How men and women experience climax — a visual summary of the body, brain, hormones, and key differences.

What Happens in the Body

Blood flow, muscle contractions, and physiological arousal.

The Brain During Orgasm

Key regions that light up during climax.

Hypothalamus — hormone release

Amygdala — emotional intensity

Nucleus accumbens — reward center

Prefrontal cortex — quiets down (less self-conscious thought)

Functional imaging shows reward, motor, and emotional areas activate during climax.

The Chemistry of Pleasure

Hormones released around orgasm and their common effects.

Oxytocin
Supports bonding and feelings of closeness after orgasm.
Prolactin
Increases after climax; tied to sexual satisfaction and refractory period.
Endorphins
Natural painkillers that boost mood and relaxation.

Questions Science Is Still Exploring

Areas under active research.

  • Why some men and women struggle to reach orgasm while others do not.
  • The roles of genetics, anatomy, and mental state.
  • Potential long-term health or evolutionary benefits.